Medicines

Can You Take ProstaFlow With Dutasteride, Nitrates or Blood Pressure Pills?

A supplement and a prescription can share a body. They should not share it by accident. This page lists what the sources say, what they leave out, and what to bring to your pharmacist.

By ProstaFlow Team at Prostaflowdaily · Medically reviewed by Dr. Al Borhan, MD, Physician · Last updated October 29, 2026 · 10 min read

Is ProstaFlow a medicine or a supplement?

It is a dietary supplement. It is not a drug, it is not FDA approved, and no supplement is. It is not meant to diagnose, treat, cure or prevent any disease. The label prints no benefit claim at all, and the seller’s pages say only that it supports prostate comfort and prostate-related wellness.

That matters for this question. A prescription was chosen for you by someone who knows your history. A capsule was chosen by you. The two are not equals, and the capsule should never push the prescription aside. If you take a medicine, keep taking it as prescribed and tell the prescriber about anything new.

What do the sources say about dutasteride?

Very little, and it is better to say so than to guess. The sources behind this website do not describe dutasteride. They do not publish a study that combines dutasteride with ProstaFlow. So there is no stated interaction, and there is no stated all-clear either.

What the sources do say is simple. Their answer to the question “Can it be taken with a prostate medication?” is to name the capsule to whoever prescribed the medication. That is a short chat with someone who knows your history, and it beats a general answer from a website.

It also helps to remember what is on the panel. There is no saw palmetto, beta-sitosterol, pygeum, zinc or lycopene. The seven rows are an amino acid stack, a B vitamin and a small amount of calcium. So the product does not copy a prescription, and it does not stand in for one.

Why do nitrate medicines get a mention?

A nitrate medicine donates nitric oxide directly. The arginine and citrulline rows feed the same signalling pathway from the starting end. So two things are acting on one system.

The site’s view is that a few hundred milligrams is likely to make a small contribution. It still says to name it at a routine review. That costs half a minute. The reply you want is the pharmacist’s, not this page’s.

What about PDE5 inhibitors?

These medicines keep a signal called cyclic GMP going for longer. Nitric oxide is what produces that signal, so the arginine and citrulline rows sit on the same chain, one step earlier. The review of how PDE5 inhibitors work in the lower urinary tract sets out the reasoning.

The site describes the interaction as theoretical at these amounts, not documented. If you have been prescribed one, for either of its uses, mention the capsule once. After that, follow your prescriber’s advice.

Can ProstaFlow affect blood pressure medicine?

The pooled evidence is a long way from one capsule. A meta-analysis of 11 trials in 387 people found that arginine lowered systolic pressure by about 5 mmHg and diastolic pressure by about 2.7 mmHg. Those trials used 4 to 24 g a day. A 2018 review of citrulline pooled five interventions and found no significant effect on blood pressure.

One capsule holds about 333 mg of arginine and 200 mg of citrulline salts. That is well below both ranges. A mention at a routine appointment is proportionate. You do not need a special visit.

How do the medicine classes line up?

Here is the whole picture in one place.

Two rows on the panel raise nothing in particular. Calcium at 18 mg is too small to change the absorption of any medicine, including the antibiotics that interact with calcium supplements at hundreds of milligrams. Niacin at 7.5 mg NE is a food-level amount.

What should you bring to the pharmacist?

Come with a short list. It saves time, and it lets the pharmacist give a specific answer.

1. Every prescription you take, with the dose.
2. Every over-the-counter product and supplement, including any multivitamin or pre-workout.
3. The ProstaFlow bottle, or a photo of the back of it, so the seven rows can be read.
4. The plan: one capsule a day, with an 8 oz glass of water, 20 to 30 minutes before a meal.
5. Your start date and your three baseline numbers, if you are running a test.

A bottle with a proprietary blend gives a pharmacist almost nothing to work with. This one prints every amount, which is the practical value of a full declaration.

What should you not do?

A few simple rules keep this safe.

• Do not stop or change a prescription because you started a supplement.
• Do not take extra capsules to chase a stronger effect. The label says not to exceed the recommended dose.
• Do not start several new things in the same fortnight. If something feels off, you will not know which one caused it.
• Do not treat new urinary symptoms as a shopping problem.

Does ProstaFlow affect a PSA test or a drug test?

Nothing on this panel has been shown to affect a PSA test. If you are having one, tell whoever orders it what you take. That is good practice with any supplement.

As for drug tests, the site states that nothing on the panel is a banned substance on any sport or workplace list. Arginine, citrulline and beta alanine are ordinary sports nutrition ingredients, and niacin is a vitamin. If a test matters for your job or sport, ask the testing body directly.

Where do these facts come from?

Label, price and policy facts come from the printed ProstaFlow label and the seller’s own pages on this website. Research facts come from the public records below.

Frequently asked questions

Our view

We think the sensible position is a quiet one. The capsule is small and the amounts are low, so a dramatic warning would be wrong. But a prescribed medicine is not a place for guesswork.

Name the capsule to whoever prescribed your medicines. Do it before you start, not after. If the answer is yes, run your test properly. If the answer is no, you have lost nothing, and the 60-day refund window is there if you have already ordered.

Last updated October 29, 2026. Medically reviewed by Dr. Al Borhan, MD, Physician, on October 16, 2026.

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